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Finding safer, more effective treatment for opioid-induced bowel dysfunction, addiction and overdose.
Aiko's patented portfolio of compounds includes naltrexone / naloxone analogs, including naltrexol, naltrexamine and naloxol derivatives. Each compound has been demonstrated to display neutral antagonist properties at the mu opioid receptor.

Compounds

AIKO-150 is the only known candidate drug suitable for co-formulation with an opioid analgesic that will confer both abuse resistance and limited side effects, particularly constipation.

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News

AIKO Biotechnology, Inc. completes second human study of lead compound

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Articles

6β-naltrexol preferentially antagonizes opioid effects on gastrointestinal transit compared to antinociception in mice
Both antagonists produced dose-related blockade of hydrocodone-induced antinociception and inhibition of gastrointestinal transit.

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AIKO Biotechnology, Inc. | 2 Union Street | Suite 501 | Portland, ME 04101