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Finding safer, more effective treatment for opioid-induced bowel dysfunction, addiction and overdose.
Aiko's patented portfolio of compounds includes naltrexone / naloxone analogs, including naltrexol, naltrexamine and naloxol derivatives. Each compound has been demonstrated to display neutral antagonist properties at the mu opioid receptor.

Compounds

AIKO-150 is the only known candidate drug suitable for co-formulation with an opioid analgesic that will confer both abuse resistance and limited side effects, particularly constipation.

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News

AIKO Biotechnology steps back to reformulate, seek financing

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Articles

The effects of the opiate neutral antagonist 6β-naltrexol in opiate dependent subjects
6βN acts as a neutral opiate antagonist, is less potent than naloxone in precipitating OWD and produces laxation.

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AIKO Biotechnology, Inc. | 2 Union Street | Suite 501 | Portland, ME 04101